The distance between Knoxville, Tennessee, and Nashville, Tennessee, is approximately 180 miles. This figure represents the shortest driving distance via commonly used interstate routes and may vary slightly depending on the specific starting and ending points within each city.
Understanding the geographical separation between these two major Tennessee cities is important for logistical planning, transportation infrastructure development, and tourism-related activities. This knowledge facilitates efficient travel, informs route optimization for freight and passenger vehicles, and supports the planning of regional events and collaborations. Historically, the accessibility between these cities has influenced trade, cultural exchange, and economic growth within the state.